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The innate immunity vaccine being discussed here at https://twitter.com/hervk102/status/1741664933887070357 which activates the HERV-K102 virus anti-virus system in foamy macrophages should block infections (sterilizing immunity) including SARS-CoV-2 and should be useful for those who got 2 or more doses of the mRNA shots. However, if the person has high blood pressure/elevated CRP which are signs of immunosenescence, the effectiveness of this innate immunity vaccine would be reduced. To remedy, ivermectin started before this vaccine, and continued for say a month might help this system get started. Alternatively or additionally, making sure one's blood vitamin D3 levels are well over 50 ng/ml plasma should reduce the risk of death. See my preprint for details.

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Thank You, Dr. Laderoute, and thank you for recommending my blog to your readers. I seek to be of useful service, addressing a broad spectrum of threats and ideas, for those who find it useful.

Vitamin K2 seems to be synergistic with vitamin-D. https://www.hindawi.com/journals/ije/2017/7454376/

K2 is supplemented at similar doses, though the K2 doses are hard to interpret, because of multiple polymeric forms with different half lives.

My wife and I use this product once daily, and have no link with the Life Extension company.

https://www.lifeextension.com/vitamins-supplements/item02334/super-k?gad_source=1&gclid=Cj0KCQiA67CrBhC1ARIsACKAa8Sr9B1XKo6rlUW5heipcSt8Ytpb20GVoRDsvKul-qaiU2jfw_yoFqwaAueZEALw_wcB

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The Japanese have already recently (Dec 26, 2023) warned about a heart failure pandemic https://mainichi.jp/english/articles/20231226/p2a/00m/0sc/047000c.

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Familiar with study but could you please clarify if this is a Significant post infection or repeated infection problem for an unvaccinated person?

Thank you in advance : )

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In the unvaccinated, unless one had a very severe infection, there are no or little spike IgG1/3 in the upper respiratory track (see references in https://www.preprints.org/manuscript/202312.0185/v1). Therefore the unvaccinated are at much lower risk of symptomatic SARS-CoV-2 so they are less likely to be infected. So with less exposure to spike protein and less exposure to SARS-CoV-2, this would highly reduce the likelihood of death (from any cause). However, those with immunosenescence (ie., high blood pressure and other comorbidities) are still at risk of more severe COVID-19 disease, but can reduce these risks by adopting healthier lifestyles and taking zinc (25 to 50 mg), lysine (2000 mg), isoflavones (60 mg) daily and if they can take ivermectin prophylactically or at least at the start of any infection. So for the healthy they might note few symptomatic infections. People with chronic fatigue syndrome may also note few symptomatic infections as their HERV-K102 virus anti-virus protector system is engaged [see Laderoute M , AIDS 2007].

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Sincerely and appreciatively thank you Dr. Laderoute : ) Have a blessed new year!

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Thank you.

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Appreciating that ivermectin has been reported to have multiple mechanisms in protecting from SARS-CoV-2 morbidity, is there concern that we would see resistance with widespread use?

I haven't seen much commentary on this in random browsing, but most of the antimicrobials in use have this concern.

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Most of the protection by ivermectin relates to a myriad of effects on the host immune system, so the answer is highly unlikely. Ivermectin was approved in the USA in 1987. We have not seen this problem in the past 37 years for any pathogen.

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