That graphic comparison is very good and helpful, Dr. Laderoute. Thank You.
(It makes me proud to have good innate immunity and take care of it by growing my vegetables outdoors and avoiding unnecessary pharmaceutical interventions.)
Thank you for sharing all of the info that you do, Dr. Laderoute. Going through your chart and it looks like you may have inadvertently mixed the memory row comparing the innate and adaptive immunity.
No the innate memory is short in the order of 6 to 12 months (of course if ADE brings in a pathogen into the foamy macrophages, then it is shorter for example, 3 months.) The adaptive which does involve recombination and "affinity maturation" tends to be long lived often decades. If you are talking about how the VE for the C19 vaccines waned in a few months, it was the innate immunity providing the protection (not the adaptive, by this I mean the IgG antibodies to spike protein.) Many papers on C19 report the loss of antibody to spike say over six months but in fact it is still "detectable" and generally can be recalled quite quickly.
That graphic comparison is very good and helpful, Dr. Laderoute. Thank You.
(It makes me proud to have good innate immunity and take care of it by growing my vegetables outdoors and avoiding unnecessary pharmaceutical interventions.)
Thank you for sharing all of the info that you do, Dr. Laderoute. Going through your chart and it looks like you may have inadvertently mixed the memory row comparing the innate and adaptive immunity.
No the innate memory is short in the order of 6 to 12 months (of course if ADE brings in a pathogen into the foamy macrophages, then it is shorter for example, 3 months.) The adaptive which does involve recombination and "affinity maturation" tends to be long lived often decades. If you are talking about how the VE for the C19 vaccines waned in a few months, it was the innate immunity providing the protection (not the adaptive, by this I mean the IgG antibodies to spike protein.) Many papers on C19 report the loss of antibody to spike say over six months but in fact it is still "detectable" and generally can be recalled quite quickly.