The HERV-K Way to Keep Coronavirus (COVID-19) at Bay
How to prevent and reverse immunosenescence to reduce your risks of COVID-19 morbidity and mortality
IMAGE: The meaning of the HERV-K acronym.
Given that the stealth omicron variant is gaining foothold internationally and may be 30% more transmissible that the original omicron variant, it is important to remember that pre-existing immunosenescence remains the key risk factor for COVID-19 severity. In addition accumulating evidence strongly suggests the pathogenesis of SARS-CoV-2 relates to SARS-CoV-2 induction of immunosenescence in foamy macrophages. Foamy macrophages which constitutively produce HERV-K102 particles are present in sebaceous glands in the oral mucosa where they are called ‘sebocytes’. The ‘waxy sebum’ that they release on day 6 by lysis provides the first line of defense against SARS-CoV-2, namely the release of HERV-K102 particles. If these HERV-K102 particles are not released from the sebocytes due to pre-existing immunosenescence, your risk of infection goes way up. [Ditto if you have sub-neutralizing antibodies induced by the COVID-19 spike protein vaccines]. Furthermore, you will be more susceptible to SARS-CoV-2 mediated morbidity and mortality if you have pre-existing immunosenescence and even high blood sugar. So to protect yourself, I am re-publishing the HERV-K protocol on Substack as my account at LinkedIn has been rescinded.
I have not updated the HERV-K protocol itself since it was published on LinkedIn on March 5, 2020 which you will note, preceded the announcement of the SARS-CoV-2 pandemic by the WHO on March 11, 2020. However, I have updated the rationale for the strategy of why one needs to prevent and/or reverse immunosenescence and in addition provide URLs for where you may consult doctors able to provide you with early treatment against COVID-19.
This knowledge and expertise on the prevention and reversion of immunosenescence and how it promotes wellness was gained when I was Lab and Research Director at Immune System Management Clinic and Lab (ISM) in Ottawa, Ontario Canada (2011 to March 2020). Using amino acid profiling algorithms I developed to monitor what was happening to macrophage innate immunity, it allowed me to define immunosenescence as the failed lytic release of HERV-K102 particles from foamy macrophages which was published in Discovery Medicine (see Laderoute M. Discovery Medicine, 2015). Uniquely, ISM had been reversing and preventing immunosenescence to promote wellness since 1998 with its ‘Aminomics’ protocol which I helped to establish as a voluntary consultant. So there is much clinical know-how and experience behind this ‘HERV-K’ protocol.
This article suggests lysine as an anti-viral and that lysine supplementation at 2000 mg daily helps to prevent SARS-CoV-2 symptomatic infection: Melano I, Kuo LL, Lo YC, Sung PW, Tien N, Su WC. Effects of basic amino acids and their derivatives on SARS-CoV-2 and influenza-A virus infection. Viruses. 2021 Jul 4;13(7):1301. doi: 10.3390/v13071301.
It should be noted that anti-inflammatories do not prevent or treat the inflammatory autoimmune diseases but only address "the symptoms". Improving life style choices (more exercise, reduce stress, eat more fruit and vegetables) but particularly stopping alcohol and sugar consumption would go along way to help address the cause of these inflammatory diseases. It is a difficult situation indeed, to resolve what the best course of action would be for someone with rheumatoid/osteo arthritis, given that longer term use of non-steroidal anti-inflammatory drugs (NSAIDs) is associated with an increased risk of heart attacks [Pepine CJ & Gurbel PA. Clinical Cardiology, July 2017]. The decision to stop statin use (statins can be considered as NSAIDs) is easier to make when used by otherwise healthy individuals. In the clinic, statins, tumeric and melatonin above 2 mgs per day prevented the ability to reverse immunosenescence. This is why I am saying one needs to 'halt' the use of anti-inflammatories (unless only used short term). Note that if you are in the hospital and in the hyperinflammatory stage with COVID-19, they will and should use potent anti-inflammatories. See FLCCC Alliance protocols.